Advanced · 10 min read
NAD+ & Cellular Energy Protocol
What the research says about NAD+ precursors, who might benefit, and how to cycle them.
- 01
Understand the evidence
NAD+ declines with age. NR and NMN raise blood NAD+ in humans; clinical outcomes are still being studied.
- 02
Start low
250–500mg per day in the morning. Assess energy and sleep for 4–6 weeks.
- 03
Pair with exercise
Exercise itself boosts NAD+ — supplements are not a substitute.
- 04
Consider metabolic tracking
A CGM can show how your energy correlates with diet and timing.
Recommended for this protocol
NAD+Moderate evidence
Nicotinamide Riboside
ExampleBio · $40/mo · ★ 4.4
- + Multiple human trials
- + Raises NAD+ reliably
- − Pricier per gram
NAD+Emerging evidence
NMN 500mg
ExampleLabs · $45/mo · ★ 4.3
- + Third-party tested
- + Sublingual option
- − Human data still limited
WearableEmerging evidence
Continuous Glucose Monitor
LevelsCo · $199/mo · ★ 4.2
- + Real-time food feedback
- − Expensive
- − 14-day sensors